TY - JOUR
T1 - Autoimmunity in Guillain-Barré syndrome associated with Zika virus infection and beyond
AU - Pinto-Díaz, Carlos A.
AU - Rodríguez, Yhojan
AU - Monsalve, Diana M.
AU - Acosta-Ampudia, Yeny
AU - Molano-González, Nicolás
AU - Anaya, Juan Manuel
AU - Ramírez-Santana, Carolina
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Autoimmune diseases share common immunopathogenic mechanisms (i.e., the autoimmune tautology), which explain the clinical similarities among them as well as their familial clustering. Guillain-Barré syndrome (GBS), an autoimmune peripheral neuropathy, has been recently associated with Zika virus (ZIKV) infection. Based on a series of cases, this review article provides a comparative analysis of GBS associated with ZIKV infection, contrasted with the general characteristics of GBS in light of the autoimmune tautology, including gender differences in prevalence, subphenotypes, polyautoimmunity, familial autoimmunity, age at onset, pathophysiology, ecology, genetics, ancestry, and treatment.
AB - Autoimmune diseases share common immunopathogenic mechanisms (i.e., the autoimmune tautology), which explain the clinical similarities among them as well as their familial clustering. Guillain-Barré syndrome (GBS), an autoimmune peripheral neuropathy, has been recently associated with Zika virus (ZIKV) infection. Based on a series of cases, this review article provides a comparative analysis of GBS associated with ZIKV infection, contrasted with the general characteristics of GBS in light of the autoimmune tautology, including gender differences in prevalence, subphenotypes, polyautoimmunity, familial autoimmunity, age at onset, pathophysiology, ecology, genetics, ancestry, and treatment.
KW - Autoimmune tautology
KW - Colombia
KW - Mycoplasma pneumoniae
KW - Polyautoimmunity
KW - Witebsky's postulates
UR - http://www.scopus.com/inward/record.url?scp=85013127749&partnerID=8YFLogxK
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U2 - 10.1016/j.autrev.2017.02.002
DO - 10.1016/j.autrev.2017.02.002
M3 - Review article
C2 - 28216074
AN - SCOPUS:85013127749
SN - 1568-9972
VL - 16
SP - 327
EP - 334
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 4
ER -